In our latest question and answer, the pharmacist discusses whether or no there is a drug interaction in between Claritin (Loratadine) and DayQuil.

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Brit asked

Is it safe to combine Claritin and DayQuil?


Claritin (loratadine) is a 2nd generation antihistamine used to treat seasonal allergies and urticaria (hives). DayQuil Cold & Flu (acetaminophen/dextromethorphan/phenylephrine) is a mix product provided to treat fever, cough and sinus congestion.

it is for sure to take both Claritin and also DayQuil with each other as there is no interaction between the two medications. Let"s take a watch at every product an ext closely.


As a 2nd generation antihistamine, Claritin (loratadine) is generally non-sedating and does not cause drowsiness. Claritin (loratadine) functions on the symptom of runny nose, itchy, watery eyes and sneezing. It come in 12 and also 24 hour formulations and also effects deserve to be felt in ~ 1 to 3 hours. The is generally a well tolerated medication through the most common side effects being headache, drowsiness, fatigue and also dry mouth. Patient with known kidney or liver disability or condition should examine with their physician or various other health care provider prior to using.


DayQuil is a mix product that contains different drugs depending on which formulation is being used. The adhering to DayQuil formulations may be available:

DayQuil HBP Cold and also Flu: paracetamol for fever/pain and Dextromethorphan for sneeze suppressantDayQuil Cold and also Flu Relief Caps: acetaminophen for fever/pain, Dextromethorphan for cough suppressant and phenylephrine because that nasal congestionDayQuil significant Cold and Flu: acetaminophen for fever/pain, Dextromethorphan for sneeze suppressant, phenylephrine because that nasal congestions and guaifenesin for expectorantDayQuil Cough and also Congestion Liquid: Dextromethorphan for sneeze suppressant and also guaifenesin for expectorantDayQuil cough Suppressant: Dextromethorphan for cough suppressant

Below, we talk about each ingredient in the above DayQuil commodities in detail:

Ingredients contained In DayQuil Products


Acetaminophen is supplied as a fever reducer and for pain. If taking DayQuil with various other drugs, it is crucial not come exceed the maximum sheep of acetaminophen. Acetaminophen has been connected with acute liver failure. Doses have to not exceed 4 grams everyday in adults. Be careful when combining with other medicines that contain paracetamol so regarding not exceed the 4 grams maximum daily dose.


Dextromethorphan is a sneeze suppressant used to aid control a cough. That is normally a fine tolerated medication. The most common side impacts that have been reported room drowsiness, nausea, vomiting and also stomach upset.


Phenylephrine is a decongestant the helps relax nasal and sinus congestion. Patients through high blood pressure should check with their medical professional or various other health treatment provider prior to taking. It deserve to increase blood pressure and also cause heart stimulation consisting of palpitations, fast heart beat and also arrhythmias. Other feasible side impacts include insomnia, anxiety, dizziness, headache and upset stomach.


Guaifenesin i am one expectorant offered to loosen mucus and also make a cough more productive. The most typical side effects are dizziness, drowsiness, headache, nausea, vomiting and stomach pain.

once taking combination products, it deserve to be rather easy to take it too lot of drug if combining with various other products. That is essential for patients to realize what they space taking and which medications are in a specific formulation. If there is any type of confusion or questions, questioning the pharmacist or one more health treatment provider for assist determining i beg your pardon product formulations room most proper for the symptom you room trying to treat.

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Taking Claritin (loratadine) and DayQuil Cold & Flu (acetaminophen/dextromethorphan/phenylephrine) is safe. Adding Claritin (loratadine) to DayQuil Cold & Flu will additionally give relief to any allergy symptoms present such together runny nose, watery, itchy eyes and sneezing.