Medically the review by Cynthia Taylor Chavoustie, MPAS, PA-C — created by Carly Vandergriendt top top June 17, 2020

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Tylenol is one over-the-counter medication provided to act mild come moderate pain and fever. It includes the active ingredient acetaminophen.

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Acetaminophen is one of the most common drug ingredients. Follow to the Food and also Drug administration (FDA), it’s discovered in much more than 600 prescription and non-prescription drugs.

Acetaminophen might be included to drugs used to treat a wide range of conditions, including the following:

allergiesarthritisbackachescold and also fluheadachesmenstrual crampsmigrainesmuscle achestoothache

In this article, we’ll look at what’s thought about a safe dosage, the signs and symptoms that might indicate an overdose, and how to protect against taking as well much.


Can you overdose on Tylenol?

It’s possible to overdose ~ above acetaminophen. This can occur if girlfriend take more than the encourage dosage.

When you take a common dose, it enters her gastrointestinal tract and is took in into her bloodstream. That starts come take effect in 45 minutes for most oral forms, or up to 2 hrs for suppositories. Eventually, it’s broken down (metabolized) in your liver and excreted in her urine.

Taking too much Tylenol changes the way it’s metabolized in your liver, result in boost in a metabolite (a by-product that metabolism) referred to as N-acetyl-p-benzoquinone imine (NAPQI).

NAPQI is toxic. In the liver, it death cells and causes irreversible organization damage. In severe cases, the can reason liver failure. This cause a chain of reaction that can lead come death.

According come a 2016 literary works review, liver failure brought about by acetaminophen overdose causes death in approximately 28 percent that cases. Among those who have liver failure, 29 percent need a liver transplant.

Those who endure an paracetamol overdose there is no needing a liver transplant may experience permanent liver damage.


What’s a for sure dosage?

Tylenol is reasonably safe when you take the recommended dose.

In general, adults deserve to take between 650 milligrams (mg) and 1,000 mg of acetaminophen every 4 come 6 hours. The FDA recommends the an adult shouldn’t take much more than 3,000 mg of acetaminophen per day uneven directed otherwise through their health care professional.

Don’t take Tylenol for an ext than 10 work in a row uneven you’ve been instructed to do so by your doctor.

The chart listed below contains more detailed dosage information for adults based upon the type of product and the quantity of acetaminophen per dose.


ProductAcetaminophenDirectionsMaximum dosageMaximum everyday acetaminophen
Tylenol constant Strength Tablets325 mg per tabletTake 2 tablets every 4 come 6 hours.10 tablets in 24 hours3,250 mg
Tylenol Extra stamin Caplets500 mg per capletTake 2 caplets every 6 hours.6 caplets in 24 hours3,000 mg
Tylenol 8 HR Arthritis pain (Extended Release)650 mg every extended-release capletTake 2 caplets every 8 hours.6 caplets in 24 hours3,900 mg

For children, the dose varies follow to weight. If your boy is under the period of 2, ask your doctor for the exactly dose.

In general, children can take around 7 mg of paracetamol per lb of your body weight every 6 hours. Children shouldn’t take much more than 27 mg of paracetamol per pound of your weight in 24 hours.

Don’t provide your kid Tylenol for more than 5 days straight unless you’ve to be instructed to perform so by her child’s doctor.

Below, you will do it find more detailed dosage charts for children based upon different assets for infants and also children.

Product: Infants’ and Children’s Tylenol oral Suspension

Acetaminophen: 160 mg per 5 milliliters (mL)


AgeWeightDirectionsMaximum dosageMaximum day-to-day acetaminophen
under 2under 24 lbs. (10.9 kg)Ask a doctor.ask a doctorask a doctor
2–324–35 lbs. (10.8–15.9 kg)Give 5 mL every 4 hours.5 doses in 24 hours800 mg
4–536–47 lbs. (16.3–21.3 kg)Give 7.5 mL every 4 hours.5 doses in 24 hours1,200 mg
6–848–59 lbs. (21.8–26.8 kg)Give 10 mL every 4 hours.5 doses in 24 hours1,600 mg
9–1060–71 lbs. (27.2–32.2 kg)Give 12.5 mL every 4 hours.5 doses in 24 hours2,000 mg
1172–95 lbs. (32.7–43 kg)Give 15 mL every 4 hours.5 sheep in 24 hours2,400 mg

Product: Children’s Tylenol Dissolve Packs

Acetaminophen: 160 mg per packet


AgeWeightDirectionsMaximum dosageMaximum daily acetaminophen
under 6under 48 lbs. (21.8 kg)Do no use.Do not use.Do no use.
6–848–59 lbs. (21.8–26.8 kg)Give 2 packets every 4 hours.5 doses in 24 hours1,600 mg
9–1060–71 lbs. (27.2–32.2 kg)Give 2 packets every 4 hours.5 doses in 24 hours1,600 mg
1172–95 lbs. (32.7–43 kg)Give 3 packets every 4 hours.5 doses in 24 hours2,400 mg

Product: Children’s Tylenol Chewables

Acetaminophen: 160 mg per chewable tablet


AgeWeightDirectionsMaximum dosageMaximum everyday acetaminophen
2–324–35 lbs. (10.8–15.9 kg)Give 1 tablet every 4 hours.5 sheep in 24 hours800 mg
4–536–47 lbs. (16.3–21.3 kg)Give 1.5 tablets every 4 hours.5 doses in 24 hours1,200 mg
6–848–59 lbs. (21.8–26.8 kg)Give 2 tablets every 4 hours.5 sheep in 24 hours1,600 mg
9–1060–71 lbs. (27.2–32.2 kg)Give 2.5 tablets every 4 hours.

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5 sheep in 24 hours2,000 mg
1172–95 lbs. (32.7–43 kg)Give 3 tablet computers every 4 hours.5 doses in 24 hours2,400 mg